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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f35747d3d08b56f87a8ad9ba782a11a2f817f4a4742f879cf131843d07b0957d' 
  AND token = 'mwgfxk9n1MXwoO2Mwo6AKDeeEdMbsEj9g9VT++Xmg3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}