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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a6ab138a4402a81740bd1dac19b23bb4d67e39575d89e17b92e441a29127f6' 
  AND token = 'eG4yVPV9Vhqbrl+r8zC8jhcc1sItbdrX0Ucx/c+dfqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}