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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '080c37f4325b5d9245e59256a04c9f267c23032656cf81379822e6b317196ee5' 
  AND token = 'UAIQkhSX09AjcNFXaII2Ehf//GTpA/aJrwf1yCL6ZWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}