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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121782b770aaa8f2286c0a460343483643e91be87b083a31c2493530d8a0405c' 
  AND token = 'e5BKqOels9+m53M3HrRPfzvitiTvqPZa16UcakPLx0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}