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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2e8f9dbd38d21d4304dc47d88897d5f452d78277685b554966a5c7a3c173c0' 
  AND token = 'fKjxBID13Opc5LxHezTGLc8PbC/fmOAqOZ4gs1NsHL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}