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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0a844a90747cbb2f350d51b229ba51fec2d2db30e84e3c3184fa548b0b1486' 
  AND token = '6myP/8V8shnMKVr6amh9TWeDuJ+3xcc/eAqOZ5OOJN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}