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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84ec3ec6265c8c6df500f59f848d1c646ac1b683be8810e4b2d30216b45926e4' 
  AND token = '000OTlHihQB4aPwPYN+yGQCgpIMICMLcjeUcPhPpQ9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}