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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292720b1c78a3e0a61f9bb67d0f654f9ee4202483f85d404b0602a11ab63816b' 
  AND token = '2lfOB7jriHDYA34qNKujD0ChGDxuf2te1WHZLscCpYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}