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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bfbae180f58b75f2efb0cb7816caf5a9bf304529604435eb4e8421d66d163c0' 
  AND token = 'gIcHbIPaDrdhTxVIQCs+fdRSp6RHnnH5ZvcIvFIi70k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}