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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36589e34822a4c27e3a63248741c98c060d0fd4197b7c2bffd7c95d177378fa6' 
  AND token = 'DCyKbuphWliF6iifzA1IeMo30XLcPXYtvduc/eck+gU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}