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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5836ecdf087f43b1a78b33b5953b245d4642d3e6cb3e7c25b0c4bb6b3fb77d49' 
  AND token = 'humqEZx/PQLkzixAwDe4Rhcl+wVwN36e4hD93gNvvOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}