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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c1a42df67cac03dcd82e002da2f2f04db615f49d6d6a707592ac9d4544613a0' 
  AND token = '8tnlYxbwIh4I+w8wlULSR4U8SwX8L7vlUMEHEM9lF3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}