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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20e358dccd3061206bfe55d18da6bba19b65fdc97a5be7be527fad711eb9e9a8' 
  AND token = 'YNycjPzUuYcaLJGj0IZVNvUKRxPLSEduDbVBlILirNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}