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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c0500dc9c612d27a52ecbc4bdbbde84b5480e2aeebabe303f057d934176049f' 
  AND token = '5u1Y3/zHAkrB1OTHnzFLJOdLsh7EDmiI89fwQG9Xnsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}