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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea350c3dc9b0ab1b06ad594afcc15f24456afa0daa427fcf791c3ec014e6b40' 
  AND token = 'bK3q0p9rtl2T0sFI2SQIOZA8sPLP+5hYDHfLP4CSWFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}