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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e504a4fc901d126134c755aa8eebe726e65e4ef3a64e47652c3d54f019126907' 
  AND token = 'OCy0RAWyo4jDwa7X1KfOcZdbbfwJT6aCGB2uL+4yk6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}