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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfed9eb7d30b1cca186fda236c552735704b3a76f08f432d844dac1585ef75c1' 
  AND token = '4resaR8BTUth1Z37HMAjX3wgdiZNZt2RtDFtpBfp98I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}