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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef1181f15cd337ff36eb124b4a83110caf8a1f164b69078e3dbe32a39c2c22c' 
  AND token = '7ss8isf/juvoMhfNG2ywM/RCgV9c12FnhOO3Ze6/tHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}