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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba7961e19f6f8efe21da801172335892c4fe05a1e776959683545a90517aeadb' 
  AND token = '2/65FD2uxarIVt9HNzuNDJbyjpMRCGzsNsuArydNnAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}