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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a468ee04441a44d52d7855420c0b2fc9d4311d3b613f651a8b1afd66a7ebe21d' 
  AND token = 'e19mJQsTrXVLzeAMy39uzV1UyfT/D8hqByEMXlsduDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}