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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99fca52c54cd59c8f63c9da453960880269c0a251edc9bb9f7c0227b3b3cacb3' 
  AND token = 'iGyhX56cmdUZdx98Sl7SOn03y4QOEsvRWVrIkLGCyCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}