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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43d68252dffc8a1792a5737fc162db50f72534928280c6b569ecdab1d1ac31c' 
  AND token = '4LPwoIvW9XQSzkvxaiVeweNL7tui+7MuCxKikpXveYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}