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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ae6d58175f74a51055d7fbc0c3629cdc1f21dafaa60aebd2c9000e6297e22b8' 
  AND token = '4MyQIBIMYjoncHEqk+9MrdI787Yg0uS+T1NzL/rvzgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}