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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd54b6a9bdbc4e1ebf1686ce7ce891f402d6d30fed7511f9e18e1ed5206134c' 
  AND token = 'nHU1Vvvy0KyCyeS53vUeu0RfDUvgbOYf/Yx2cHJN0dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}