SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b6537031aa7efcee544146efca1da66ea2b7b3149917fd50ba8497ee00e4082' 
  AND token = 'sPm1xpgF6FIl9mGmoqvUUaty+h+/1PoXTBFY0wbRRZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}