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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d10c19c696a1467ec6ff0b5b7f0539bf34d4f4d50f2a3a388ea776cdf586f18' 
  AND token = 'wszT3RVwV3/RsLb+JRgkLR7pCpXiAfCx3GODYUdoS+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}