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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb02e3701f46eb1ff48c0f0d850ed5ea12d592d5d787e39bbd9a992830100b15' 
  AND token = 'B8Fa458oEVZ9Ggd/kiYiy7SnqbmZj+HANUnEZG0qc5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}