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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cceeb175ddd10c2a2f3039610e7f26cce922253cdd192d186a8f9810b9aa171' 
  AND token = 'OBgm2ZTkXQZeG/LD/qBzi+OOrpDLA6STd8z5LAr+WFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}