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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45555ac4e881f6976a86d3d93c88c695287b3326fc3e1299581207169d775dd' 
  AND token = 'HLNfPOIkmz0gFrVlsElWIL9CG1efUkphO4M8aN9mwrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}