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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de203ed625a86c4cb202a2717e31547c60600d1f3f2cdcfbc31ee396f4fe2706' 
  AND token = 'dx/kU4id38m9/3xY8q7LMz5PtZyuOrw88VE1+Z3EWdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}