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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65c6948c2bd4da71110c1f2f8ec79ba4d3b92a719e8743e53b204c781651a09' 
  AND token = '3nd53ePNPGOMXIusPYq4+0th7dBMjtrPXh3mfBd2oC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}