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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2f5926680ad4d6569cf3c7c676396f48edfe73b83ccb6ee1aa53c08164cc50' 
  AND token = 'Dyecrgy/iIckP668KD/eeeDU5MKGjm/6WNXgXXvSL1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}