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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b44f4f0b09afde9d28fbdc6136317841956d3154e2e5058bde7652382abe2081' 
  AND token = 'JOiMNxoeZulN8wjAKqyfhcwShMif2ev82JFNwDcmMys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}