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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d3941a293602a0c4ffc1b78e3bdcbfd910471c8307fee2697e42ffc2b85d097' 
  AND token = 'V7x6n83XpBlHiyR8qdD20oPYMBfvMo5VmnmtE3hr63U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}