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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65795116f8d141d5e0fcdbe7ad59f8c6a7cd28880f0ba3542d1eae9c46df9431' 
  AND token = 'LPAwSF9XC+ECXyPOZxi2P+8T7v9m2wT8yT7nb9bYLao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}