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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab29e9bf91545ed8323a60b4ba877e8fca9507c41bec1186c4a4e5c0d0aa196b' 
  AND token = 'OPdD1c0uhAJzH1ZI0fzbj2Q+/Cgys0ZQ92O7UZVKznk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}