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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dcc9cecdfe870d01f8aa8cb92b40e40434c4d7c2df01d16573091b9912cc680' 
  AND token = '0gUQAFhgmjTr68I+wTDnBgYDKdqhXjW2sB2fenxcGE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}