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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a7a70d42b50e7ec64cb3bdb4bb2a4d3b52106a794bca51a35e810080ea8af47' 
  AND token = '4poonbp/wQC33xzGlagCgMQKq5/FkMsG4aWZp5bDq6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}