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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b101be7527f9eeca6d3c52dfa84fb8a34628544a396d733e036e40672a0681c' 
  AND token = '5HE8Ix1tgt74aFnbiLU6oyGs5BM6/tLREElAdlnYQYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}