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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216d5069ba76c5511be63b41e22db9c6bad8a0ea5aaf2b2550ad4060ff8360cc' 
  AND token = 'xcODIY8h4xYMXmxyf+XRKxxbKxbKHAI3dHhgm6uAALo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}