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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b409faa114de169fab67a6b0114aec7f950b225275266494a35cd15f246017' 
  AND token = 'IVFgarIao4JwH5W8ak0mgCrULF0gW/imyKms6N27uaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}