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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c27fe392fdc29bfb217ed851940ce819b0b769da1a053dbb8ef334c3ef7f764e' 
  AND token = 'CMLHgTSK1GXr3og7w7d2GwHwEmPBhLVVA6zJre2QyDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}