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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac66369223a3be6ef03f4f6250cf69663f76a0204c0d2d955047637f76a37a2' 
  AND token = 'VjdcPTidgw/mMw3utSyyzoz6iobkxU7RWkj6DoF44S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}